.jpg "Marilena Tauro, PhD photo")
Scientist
H Lee Moffitt Cancer Center
Marilena Tauro, PhD, Research Scientist III, Tumor Biology Department, H Lee Moffitt Cancer Center & Research Institute
Complete List of Published Work in MyBibliography: https://www.ncbi.nlm.nih.gov/myncbi/1DAIC-XnDMa5Cg/bibliography/public/
1. Breast Cancer Treatment.
a. Tauro M, et al. Bone seeking matrix metalloproteinase-2 inhibitors prevent bone metastatic breast cancer growth. Molecular Cancer Therapeutics, 16(3) March 2017. PMCID: PMC5337166.
b. Tauro M et al., Cutting to the chase: how matrix metalloproteinase-2 activity controls breast- cancer- to-bone metastasis, Cancers 2018, 10(6), 185. PMCID: PMC6025260.
b. Tauro M, et al., (2014) New approaches to selectively target cancer associated matrix metalloproteinase activity. Cancer & Metastasis Reviews, Dec;33(4):1043-57. PMID: 25325988 (65 citations to date)
2. Multiple Myeloma.
a. Shay G, Tauro M, Laghezza A, Tortorella P, Hazlehurst L, Sullivan D and Lynch CC (2017). Selective targeting of the multiple myeloma bone microenvironment with MMP-2 inhibitors. Oncotarget. Oncotarget. 8(26):41827-41840. PMCID: PMC5522031. (12 citations to date)
b. Ember SW, Lambert QT,Berndt N, Gunawan S, Ayaz M, Tauro M, Zhu JY, Cranfill PJ, Greninger P, Lynch CC, Benes C, Lawrence HR,Reuther GW, Lawrence NJ and Schonbrunn E. (2017) Potent dual BET bromodomain-kinase inhibitors as value added multi-targeted chemical probes and cancer therapeutics. Mol. Cancer Ther. 16 (6), 1054-1067. PMCID: PMC5457702. (27 citations to date).
3. Drug Discovery.
a. Tauro M, et al. Catechol-based matrix metalloproteinase inhibitors with additional anti-oxidative activity. Journal of Enzyme Inhibition and Medicinal Chemistry, 2016, PMID: 27556138.
b. Tauro M, et al. Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII. Bioorganic & medicinal chemistry letters. 2014; 24(8): 1941-3. PMID: 24650641.
d. Tauro et al. Design, synthesis and biological evaluation ofa class of bioisosteric oximes of the novel dual Peroxisome Proliferator-Activated Receptor α/γ ligand LT175. Eur J Med Chem. 2015 Jan 27;90: 583-9. PMID: 25497132.