Associate Professor
Mayo Clinic Arizona
My name is Marta Chesi and I am an Associate Professor of Medicine at Mayo Clinic, Arizona. In collaboration with Leif Bergsagel I have defined the recurrent genomic abnormalities affecting patients with multiple myeloma, which are used worldwide for patient’s stratification.
I have also generated an orthotopic, immunocompetent, clinically predictive genetically engineered mouse model of myeloma sensitive to IMiDs, Vk*MYC-hCRBN, which we have extensively used as a platform for testing the role of oncogenic mutations in myeloma progression, to inform drug development and to optimize anti-myeloma immunotherapy.