Head of department hematology
Amsterdam UMC
Sonja Zweegman, MD, PhD, is head of the Department of Hematology, Amsterdam UMC in Amsterdam, the Netherlands. She is chair of the HOVON Myeloma Working Group.
Her clinical research is focused on the improvement of the treatment of patients with Multiple Myeloma. She is the principal investigator of several (inter)national clinical trials in the elderly aiming at personalized treatment based on the level of frailty. In order to reach that goal, she investigates whether functional geriatric assessments and biological markers of frailty, such as senescence and sarcopenia, are better predictors for the feasibility of therapy. Furthermore, she co-leads the myeloma translational research group, which is embedded within the Department of Hematology, in order to integrate scientific research with care. The research is dedicated to improve immune therapy of Multiple Myeloma. Firstly, by investigating the mechanism of action of immune therapy, being exemplified by revealing the long term immune-regulatory effects of anti-CD38 monoclonal antibodies, and the biological background of immune therapy resistance. Secondly, by developing novel treatment strategies, such as dual CAR-T cell therapy. She is a co-author of more than 300 peer-reviewed papers and several book chapters.
Thursday, September 28, 2023
11:55 AM – 12:30 PM EEST