Professor
University of Arkasas Medical Sciences
Dr. Fenghuang (Frank) Zhan is the Research Director of Myeloma Center at UAMS. His main expertise lies in the area of genomics and molecular/cellular biology, as well as mouse models of multiple myeloma (MM). His group has a long history of identifying treatment approaches to overcome drug resistance in MM by using genomic and genetic tools from a very large database of clinical samples and mouse models. His major contributions are (1) Defining the genetic chaos in myeloma. (2) Develop novel treatments to overcome drug resistance in multiple myeloma. (3) Understanding of tumor kinetics and microenvironmental control of myeloma growth. (4) Using gene expression profiling and proteomics to identify high-risk disease and guide therapeutic interventions. As PI, he has received many grants from National Institutes of Health / National Cancer Institute (NIH/NCI), Department of Defense (DOD), Leukemia and Lymphoma Society, Multiple Myeloma Research Foundation, Riney Foundation, Myeloma CROWD, and others. He has published over 160 peer reviewed papers including in the prestigious journals: NEJM, Science, Cancer Cell, Blood, JCI, etc.